The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2012
Filed:
Nov. 14, 2002
Guohua Chen, Sunnyvale, CA (US);
Paul R. Houston, Hayward, CA (US);
Lothar Walter Kleiner, Los Altos, CA (US);
John J. Spaltro, Asbury, NJ (US);
Guohua Chen, Sunnyvale, CA (US);
Paul R. Houston, Hayward, CA (US);
Lothar Walter Kleiner, Los Altos, CA (US);
John J. Spaltro, Asbury, NJ (US);
Durect Corporation, Cupertino, CA (US);
Abstract
Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.