The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2012
Filed:
May. 23, 2008
Catherine Rachel Ettinger, Bethesda, MD (US);
Peter E. Lipsky, Rockville, MD (US);
Warren J. Leonard, Bethesda, MD (US);
Rosanne Spolski, Ellicott City, MD (US);
Herbert C. Morse, Iii, Rockville, MD (US);
Catherine Rachel Ettinger, Bethesda, MD (US);
Peter E. Lipsky, Rockville, MD (US);
Warren J. Leonard, Bethesda, MD (US);
Rosanne Spolski, Ellicott City, MD (US);
Herbert C. Morse, III, Rockville, MD (US);
Abstract
The invention provides a method for promoting differentiation of a mature naïve B cell or a B cell progenitor into a memory B cell or a plasma cell. The method comprises (a) contacting a population of cells comprising a mature naïve B cell or a B cell progenitor with an agent that activates at least one of JAK1, JAK3, STAT3, STAT5A or STAT5B; wherein the population of cells optionally is contacted with an antigen, and (b) isolating the memory B cell or plasma cell.