The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2012

Filed:

Jul. 17, 2008
Applicants:

Mary M. Bendig, Villanova, PA (US);

Olivier J. Leger, Hertfordshire, GB;

Jose Saldanha, Enfield, GB;

Tarran S. Jones, Radlett, GB;

Ted A. Yednock, Fairfax, CA (US);

Inventors:

Mary M. Bendig, Villanova, PA (US);

Olivier J. Leger, Hertfordshire, GB;

Jose Saldanha, Enfield, GB;

Tarran S. Jones, Radlett, GB;

Ted A. Yednock, Fairfax, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury.


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