The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2012
Filed:
Mar. 28, 2008
Peter John Bonitatibus, Jr., Saratoga Springs, NY (US);
Amit Mohan Kulkarni, Clifton Park, NY (US);
Andrew Soliz Torres, Troy, NY (US);
Ying Zhou, Niskayuna, NY (US);
Chiaki Treynor, Palo Alto, CA (US);
Daniel Eugene Meyer, Rexford, NY (US);
Peter John Bonitatibus, Jr., Saratoga Springs, NY (US);
Amit Mohan Kulkarni, Clifton Park, NY (US);
Andrew Soliz Torres, Troy, NY (US);
Ying Zhou, Niskayuna, NY (US);
Chiaki Treynor, Palo Alto, CA (US);
Daniel Eugene Meyer, Rexford, NY (US);
General Electric Company, Niskayuna, NY (US);
Abstract
Composition of non-radioactive traceable metal isotope-enriched nanoparticles, and methods of their use for determining in-vivo biodistribution are provided. The methods comprise the steps of: (a) introducing the nanoparticles into the biological material, wherein the nanoparticles comprise at least one inorganic core, and the inorganic core comprises at least two metal isotopes in a predetermined ratio; wherein at least one metal isotope is enriched non-radioactive traceable metal isotope and (b) determining the distribution of the nanoparticles in the biological material based on the predetermined ratio of the metal isotopes.