The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2012

Filed:

Feb. 16, 2007
Applicants:

James Halbrook, Woodinville, WA (US);

Edward A. Kesicki, Bothell, WA (US);

Laurence E. Burgess, Boulder, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Charles T. Eary, Longmont, CO (US);

Justin G. Schiro, Firestone, CO (US);

Hongmei Huang, Broomfield, CO (US);

Michael Evans, Louisville, CO (US);

Yongxin Han, Longmont, CO (US);

Inventors:

James Halbrook, Woodinville, WA (US);

Edward A. Kesicki, Bothell, WA (US);

Laurence E. Burgess, Boulder, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Charles T. Eary, Longmont, CO (US);

Justin G. Schiro, Firestone, CO (US);

Hongmei Huang, Broomfield, CO (US);

Michael Evans, Louisville, CO (US);

Yongxin Han, Longmont, CO (US);

Assignee:

Luitpold Pharmaceuticals, Inc., Shirley, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/86 (2006.01); C07D 405/04 (2006.01); C07D 219/06 (2006.01); C07D 219/16 (2006.01); C07D 401/06 (2006.01); C07D 405/12 (2006.01); C07D 471/04 (2006.01); A61K 31/35 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.


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