The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2012
Filed:
May. 16, 2008
Shinji Takeoka, Tokyo, JP;
Yosuke Obata, Tokyo, JP;
Shoji Tajima, Tokyo, JP;
Manabu Ito, Tokyo, JP;
Atsushi Mizuno, Tokyo, JP;
Natsuko Nishiyama, Tokyo, JP;
Yoshito Takeuchi, Tokyo, JP;
Shinji Takeoka, Tokyo, JP;
Yosuke Obata, Tokyo, JP;
Shoji Tajima, Tokyo, JP;
Manabu Ito, Tokyo, JP;
Atsushi Mizuno, Tokyo, JP;
Natsuko Nishiyama, Tokyo, JP;
Yoshito Takeuchi, Tokyo, JP;
Waseda University, Tokyo, JP;
JCR Pharmaceuticals Co. Ltd., Ashiya-Shi, JP;
Abstract
The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. The molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.