The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2012

Filed:

Dec. 22, 2008
Applicants:

Jean-pierre Begue, Paris, FR;

Danielle Bonnet-delpon, Paris, FR;

Benoît Crousse, Igny, FR;

Fabienne Grellepois, Reims, FR;

Constance Chollet, Montrouge, FR;

Jacques Fahy, Labruguiere, FR;

Céline Mordant, Saint Julien En Genevois, FR;

Inventors:

Jean-Pierre Begue, Paris, FR;

Danielle Bonnet-Delpon, Paris, FR;

Benoît Crousse, Igny, FR;

Fabienne Grellepois, Reims, FR;

Constance Chollet, Montrouge, FR;

Jacques Fahy, Labruguiere, FR;

Céline Mordant, Saint Julien En Genevois, FR;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/337 (2006.01); C07D 493/16 (2006.01); C07D 321/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with Band Bselected from C═O, CHOH and CH, as well as to their use in treating cancer and to their preparation method.


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