The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2012
Filed:
Feb. 07, 2006
Chemical exchange saturation transfer based mri using reporter genes and mri methods related thereto
Peter C. M. Van Zijl, Ellicott City, MD (US);
Assaf A. Gilad, Bethesda, MD (US);
Jeff Bulte, Fulton, MD (US);
Michael T. Mcmahon, Baltimore, MD (US);
Raman Venu, Ellicott City, MD (US);
Paul T. Winnard, Jr., Glen Burnie, MD (US);
Peter C. M. van Zijl, Ellicott City, MD (US);
Assaf A. Gilad, Bethesda, MD (US);
Jeff Bulte, Fulton, MD (US);
Michael T. Mcmahon, Baltimore, MD (US);
Raman Venu, Ellicott City, MD (US);
Paul T. Winnard, Jr., Glen Burnie, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
Featured are a new class of reporter genes including reporter compositions as well as methods, MRI systems and MRI imaging kits related thereto. The genes according to the present invention provide MR contrast when the sample/subject is irradiated at a specific off-resonance radio-frequency (RF frequency), where the contrast mechanism utilizes chemical exchange saturation transfer (CEST) technique for imaging.