The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2012
Filed:
Oct. 10, 2006
Roman Kischel, Karlsfeld, DE;
Tobias Raum, München, DE;
Bernd Schlereth, Germering, DE;
Doris Rau, Unterhaching, DE;
Ronny Cierpka, München, DE;
Peter Kufer, Moosburg, DE;
Roman Kischel, Karlsfeld, DE;
Tobias Raum, München, DE;
Bernd Schlereth, Germering, DE;
Doris Rau, Unterhaching, DE;
Ronny Cierpka, München, DE;
Peter Kufer, Moosburg, DE;
Micromet AG, Munich, DE;
Abstract
The present invention relates to uses of bispecific antibodies exhibiting cross-species specificity for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of the same in non-human species and humans. The present invention moreover relates to methods for evaluating the in vivo safety and/or activity and/or pharmacokinetic profile of said bispecific anti-bodies exhibiting cross-species specificity. The present invention also relates to methods of measuring the biological activity and/or efficacy of such bispecific antibodies exhibiting cross-species specificity. In addition, the present invention relates to pharmaceutical compositions comprising bispecific single chain antibodies exhibiting cross-species specificity and to methods for the preparation of pharmaceutical compositions comprising said bispecific single chain antibodies exhibiting cross-species specificity for the treatment of diseases.