The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2012

Filed:

Mar. 10, 2010
Applicants:

Shaker Mousa, Wynantskill, NY (US);

Dahui Liu, Wynnewood, PA (US);

Inventors:

Shaker Mousa, Wynantskill, NY (US);

Dahui Liu, Wynnewood, PA (US);

Assignee:

PolyMedix,Inc., Radnor, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/65 (2006.01); A61K 31/165 (2006.01);
U.S. Cl.
CPC ...
Abstract

Aspects of the present invention relate to compounds and methods useful in modulating angiogenesis and methods of treating or preventing diseases associated with angiogenesis by administering a polycationic compound. The present invention relates to methods of use and compositions for inhibiting angiogenesis-mediated disorders in mammals including animals and humans. Additionally, this invention relates to the combined use of polycations with other anti-angiogenesis agents for the treatment of different angiogenesis-mediated disorders. Additionally, those polycationic compounds can be used with various anti-inflammatory and cytotoxic agents as well as with radio-therapeutic agents in cancer patients to prevent and treat tumor growth and metastasis.


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