The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2012
Filed:
Sep. 08, 2008
Benjamin M. Cohen, Cranford, NJ (US);
Daniel J. Kumke, Colts Neck, NJ (US);
Lushi Tan, Edison, NJ (US);
Aaron S. Cote, West Windsor, NJ (US);
Benjamin M. Cohen, Cranford, NJ (US);
Daniel J. Kumke, Colts Neck, NJ (US);
Lushi Tan, Edison, NJ (US);
Aaron S. Cote, West Windsor, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to a process for the production of crystalline particles of a glucagon receptor antagonist compound. The process includes the steps of generating microseeds and subjecting the microseeds to a crystallization process. The resulting crystalline particles have a mean particle size of less than about 100 mm. The present invention also provides for a pharmaceutical composition which includes the crystalline particles produced by the method described herein and a pharmaceutically acceptable carrier.