The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2012

Filed:

May. 12, 2011
Applicants:

Andreas Schoop, Neuried, DE;

Alexander Backes, Kufstein, AT;

Joachim Vogt, Munich, DE;

Lars Neumann, Kottgeisering, DE;

Jan Eickhoff, Munich, DE;

Stefan Hannus, Munich, DE;

Kerrin Hansen, Gilching, DE;

Peter Amon, Gilching, DE;

Igor Ivanov, Markt Indersdorf, DE;

Matthias Borgmann, Stamberg, DE;

Chase Smith, Rutland, MA (US);

Arthur F. Kluge, Lincoln, MA (US);

Krishan Murthi, Andover, MA (US);

Rebecca Casaubon, Cambridge, MA (US);

Inventors:

Andreas Schoop, Neuried, DE;

Alexander Backes, Kufstein, AT;

Joachim Vogt, Munich, DE;

Lars Neumann, Kottgeisering, DE;

Jan Eickhoff, Munich, DE;

Stefan Hannus, Munich, DE;

Kerrin Hansen, Gilching, DE;

Peter Amon, Gilching, DE;

Igor Ivanov, Markt Indersdorf, DE;

Matthias Borgmann, Stamberg, DE;

Chase Smith, Rutland, MA (US);

Arthur F. Kluge, Lincoln, MA (US);

Krishan Murthi, Andover, MA (US);

Rebecca Casaubon, Cambridge, MA (US);

Assignee:

Forma Therapeutics, Inc., Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/505 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.


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