The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2012
Filed:
Sep. 28, 2007
Keiji Nakamura, Suita, JP;
Hiroyuki Nakagawa, Osaka, JP;
Yoko Kan, Osaka, JP;
Dainippon Sumitomo Pharma Co., Ltd., Osaka, JP;
Sumitomo Chemical Company, Limited, Tokyo, JP;
Abstract
The present invention relates to a bicyclic pyrimidine compound of the following formula (I) or a salt thereof. wherein Ris lower alkyl, cyclic lower alkyl. etc.; Ris H, lower alkyl, lower alkenyl, etc.; Ris H, lower alkyl, lower alkenyl, etc.; X is O, S or —N(R)—; Ris H or lower alkyl; or Rand Rmay combine each other to form cyclic amino; Y is amido, keto, sulfonyl, etc.; Ris H or lower alkyl; Z is O or S; m and n are 1 or 2. Said compound (I) or a salt thereof have MGAT inhibitory activity, and are useful as an agent for treatment or prophylaxis of adiposity, metabolic syndromes, hyperlipidemia, hyper neutral lipemia, hyper VLDL-mia, hyper fatty acidemia, diabetes mellitus, arteriosclerosis.