The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2012

Filed:

Oct. 02, 2007
Applicants:

Qingqi Chen, Chapel Hill, NC (US);

Jonathan Daniel Heller, San Francisco, CA (US);

Rocio Alejandra Lopez, Raleigh, NC (US);

Amanda Jean Morris, Graham, NC (US);

Inventors:

Qingqi Chen, Chapel Hill, NC (US);

Jonathan Daniel Heller, San Francisco, CA (US);

Rocio Alejandra Lopez, Raleigh, NC (US);

Amanda Jean Morris, Graham, NC (US);

Assignee:

Erimos Pharmaceuticals LLC, Houston, TX (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/445 (2006.01); A61K 31/341 (2006.01); A61K 31/426 (2006.01); A61K 31/165 (2006.01); A61K 31/132 (2006.01); A61K 31/085 (2006.01); C07D 277/24 (2006.01); C07D 307/52 (2006.01); C07D 211/06 (2006.01); C07D 241/04 (2006.01); C07C 271/46 (2006.01); C07C 271/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to nordihydroguaiaretic acid derivative compounds, namely, butane bridge modified nordihydroguaiaretic acid (NDGA) compounds and butane bridge modified tetra-O-substituted NDGA compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, metabolic diseases, such as diabetes and hypertension, or a proliferative disease, such as diverse types of cancers.


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