The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2012
Filed:
Nov. 08, 2007
Yen-tung Luan, Chelmsford, MA (US);
Wenge Wang, North Chelmsford, MA (US);
Ryan Nolan, Stoneham, MA (US);
Denis Drapeau, Salem, NH (US);
Yen-Tung Luan, Chelmsford, MA (US);
Wenge Wang, North Chelmsford, MA (US);
Ryan Nolan, Stoneham, MA (US);
Denis Drapeau, Salem, NH (US);
Wyeth LLC, Madison, NJ (US);
Abstract
This invention relates to methods for rationally designing cell culture media for use in cell cultures, e.g., cell cultures employed in polypeptide production; cell culture media designed with the disclosed methods; methods of producing a polypeptide of interest, e.g., an antibody, using such media; polypeptides produced using the methods and media disclosed herein; and pharmaceuticals compositions containing such polypeptides. The rationally designed media contain a concentration of an amino acid that is calculated for use in cell mass, a concentration of the amino acid that is calculated for use in cell maintenance, and a concentration of the amino acid that is calculated for incorporation into the polypeptide of interest.