The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2012
Filed:
Oct. 19, 2010
Joel A. Edwards, Las Flores, CA (US);
Wenhu Huang, San Digeo, CA (US);
Charles Montgomery, Jay, OK (US);
NI Nancy Qian, San Diego, CA (US);
Zheng-zheng Shi, The Woodlands, TX (US);
Mary Jean Sparks, Magnolia, TX (US);
Peter Vogel, The Woodlands, TX (US);
Mindy Oox, Houston, TX (US);
Joel A. Edwards, Las Flores, CA (US);
Wenhu Huang, San Digeo, CA (US);
Charles Montgomery, Jay, OK (US);
Ni Nancy Qian, San Diego, CA (US);
Zheng-Zheng Shi, The Woodlands, TX (US);
Mary Jean Sparks, Magnolia, TX (US);
Peter Vogel, The Woodlands, TX (US);
Mindy Oox, Houston, TX (US);
Lexicon Genetics, Inc., The Woodlands, TX (US);
Abstract
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO227, PRO233, PRO238, PRO1328, PRO4342, PRO7423, PRO10096, PRO21384, PRO353 or PRO1885 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.