The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2012

Filed:

Jan. 12, 2010
Applicants:

Alan D. Snow, Lynnwood, WA (US);

Qubai HU, Kirkland, WA (US);

Judy A. Cam, Bellevue, WA (US);

Inventors:

Alan D. Snow, Lynnwood, WA (US);

Qubai Hu, Kirkland, WA (US);

Judy A. Cam, Bellevue, WA (US);

Assignee:

ProteoTech, Inc., Kirkland, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 33/00 (2006.01); C07C 49/00 (2006.01); C07C 209/00 (2006.01); C07C 211/00 (2006.01); C07C 233/00 (2006.01); C07C 239/00 (2006.01); C07C 275/00 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable salts and their use in the modulation of Sirtuin 1 (Sirt1) and there use in neuroprotection for subject suffering from neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease, including Parkinson's plus diseases such as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration and dementia with Lewy bodies, and in the manufacture of medicaments for such Sirt1 modulation and neuroprotection.


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