The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2012

Filed:

Jul. 06, 2010
Applicants:

Debra Ainge, Leicestershire, GB;

Eric Merifield, Leicestershire, GB;

Colin Thomson, Leicestershire, GB;

Michael Butters, Bristol, GB;

Ravi Ramakrishnan, Bangalore, IN;

Ravi Naidu Rayapati, Bangalore, IN;

Parhalad Ray Sharma, Bangalore, IN;

Inventors:

Debra Ainge, Leicestershire, GB;

Eric Merifield, Leicestershire, GB;

Colin Thomson, Leicestershire, GB;

Michael Butters, Bristol, GB;

Ravi Ramakrishnan, Bangalore, IN;

Ravi Naidu Rayapati, Bangalore, IN;

Parhalad Ray Sharma, Bangalore, IN;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/30 (2006.01); C07D 209/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): X is ═O, ═N—OH or ═N—OC(O)Me; Y is hydrogen, PhS- or p-chlorophenylsulfanyl; Z is hydrogen or —CHCOORwherein Ris selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.


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