The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2012

Filed:

Nov. 09, 2007
Applicants:

Torbjorn Lundstedt, Uppsala, SE;

Elisabeth Seifert, Uppsala, SE;

Per Lek, Uppsala, SE;

Arne Boman, Uppsala, SE;

Inventors:

Torbjorn Lundstedt, Uppsala, SE;

Elisabeth Seifert, Uppsala, SE;

Per Lek, Uppsala, SE;

Arne Boman, Uppsala, SE;

Assignee:

Anamar AB, , SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); C07D 209/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are described Compounds of formula (I) in which Rto Rare independently selected from hydrogen, halogen, trihaloalkyl, alkyl having 1, 2, 3, 4 or 5 carbon atoms, electron donor groups selected from alkoxy having 1, 2, 3, 4 or 5 carbon atoms, trihaloalkoxy, hydroxy or amino, electron acceptor groups selected from cyano, sulphonic, nitro, or amide; Ris an optionally substituted phenyl, benzyl or cyclohexyl group; Ris selected from amino, substituted amino or guanidino groups, Z is a saturated or unsaturated Chydrocarbon chain, and salts thereof. A process for their preparation and compositions containing them are also described. The Compounds are either agonists or antagonists of a specific adenosine receptor or a number of adenosine receptors and have usefulness for the treatment of inflammation, arthritic conditions, rheumatoid arthritis, osteoarthritis, mental disorders, or for inducing central nerve regeneration.


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