The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2012

Filed:

May. 15, 2009
Applicants:

Alison O'neill, Boston, MA (US);

Douglas B. Jacoby, Wellesley, MA (US);

Abdellah Sentissi, Dover, MA (US);

Kamala Kesavan, West Roxbury, MA (US);

E. Michael Egan, Brookline, MA (US);

Laura Sen, Legal Representative, Brookline, MA (US);

Inventors:

Alison O'Neill, Boston, MA (US);

Douglas B. Jacoby, Wellesley, MA (US);

Abdellah Sentissi, Dover, MA (US);

Kamala Kesavan, West Roxbury, MA (US);

E. Michael Egan, Brookline, MA (US);

Laura Sen, legal representative, Brookline, MA (US);

Assignee:

Morphotek, Inc., Exton, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include systemic (e.g., intravenous) administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment, inhibition and/or reduction, and detection of metastases in the brain. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.


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