The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2012

Filed:

Feb. 08, 2011
Applicants:

Lance Bare, Walnut Creek, CA (US);

James J. Devlin, Lafayette, CA (US);

Frits R. Rosendaal, KC Wasenaar, NL;

Pieter H. Reitsma, TJ Leiden, NL;

Irene D. Bezemer, Utrecht, NL;

Inventors:

Lance Bare, Walnut Creek, CA (US);

James J. Devlin, Lafayette, CA (US);

Frits R. Rosendaal, KC Wasenaar, NL;

Pieter H. Reitsma, TJ Leiden, NL;

Irene D. Bezemer, Utrecht, NL;

Assignee:

Celera Corporation, Alameda, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular VT and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.


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