The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2012
Filed:
Nov. 13, 2009
Andreas Buthe, Steinfurt, DE;
Andreas Hafner, Gelterkinden, CH;
Franz Kaufmann, Freiburg, DE;
Esther Gabor, Zwingenberg, DE;
Guido Meurer, Seeheim-Jugenheim, DE;
Jürgen Eck, Heppenheim, DE;
Gordon Bradley, Liestal, CH;
Andreas Buthe, Steinfurt, DE;
Andreas Hafner, Gelterkinden, CH;
Franz Kaufmann, Freiburg, DE;
Esther Gabor, Zwingenberg, DE;
Guido Meurer, Seeheim-Jugenheim, DE;
Jürgen Eck, Heppenheim, DE;
Gordon Bradley, Liestal, CH;
BASF SE, Ludwigshafen, DE;
Abstract
The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pharmaceutical forms with a hydrophobin-containing solution to modify the pharmaceutical properties of the galenic form. In a preferred embodiment of the invention hydrophobins are used to improve the properties of a pharmaceutical composition, e.g. to act as a surfactant or to increase resistance to disintegration of the galenic forms to achieve a retarded drug release. The galenic form to be modified by the use of surface active proteins as excipients can be capsules, tablets, pills, microparticles, vesicles, and suppositories, although further galenic forms are envisioned. The surface active proteins used for the purpose of present invention can either be isolated from their respective natural source or prepared by recombinant techniques and expression in a suitable host.