The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
Sep. 27, 2007
Kunihiko Higashiura, Kato, JP;
Takashi Ogino, Kato, JP;
Kazuhito Furukawa, Kato, JP;
Yuriko Yamazaki, Kato, JP;
Kunihiko Higashiura, Kato, JP;
Takashi Ogino, Kato, JP;
Kazuhito Furukawa, Kato, JP;
Yuriko Yamazaki, Kato, JP;
Nippon Zoki Pharmaceutical Co., Ltd., Osaka-Shi, JP;
Abstract
The present invention provides a compound, an oxepin derivative having excellent histamine receptor antagonistic action, which is useful as an antihistamine. The oxepin derivative of the present invention has a potent histamine receptor antagonistic action. Further, the compound of the present invention shows low intracerebral migration even when a mouse that is orally administered with the compound is subjected to an intracerebral receptor binding test, so that the compound has preferred properties of alleviating side effects in the central nervous system, such as drowsiness. The oxepin derivative of the present invention is very useful as a novel antihistamine having smaller side effects in the central nervous system, such as drowsiness.