The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
Jun. 14, 2010
Applicants:
Shaomeng Wang, Saline, MI (US);
Dongguang Qin, Auburn Hills, MI (US);
Jianyong Chen, Ann Arbor, MI (US);
Shanghai Yu, Ann Arbor, MI (US);
Inventors:
Shaomeng Wang, Saline, MI (US);
Dongguang Qin, Auburn Hills, MI (US);
Jianyong Chen, Ann Arbor, MI (US);
Shanghai Yu, Ann Arbor, MI (US);
Assignee:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).