The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
Sep. 25, 2008
James M. Balkovec, Martinsville, NJ (US);
Phieng Siliphaivanh, Newtown, MA (US);
Frances A. Bouffard, Scotch Plains, NJ (US);
Roland A. Bouffard, Legal Representative, Scotch Plains, NJ (US);
Michael R. Peel, Chapel Hill, NC (US);
Weiming Fan, Chapel Hill, NC (US);
Ahmed Mamai, Raleigh, NC (US);
Sarah Dimick Gray, Eagan, MN (US);
James M. Balkovec, Martinsville, NJ (US);
Phieng Siliphaivanh, Newtown, MA (US);
Frances A. Bouffard, Scotch Plains, NJ (US);
Roland A. Bouffard, legal representative, Scotch Plains, NJ (US);
Michael R. Peel, Chapel Hill, NC (US);
Weiming Fan, Chapel Hill, NC (US);
Ahmed Mamai, Raleigh, NC (US);
Sarah Dimick Gray, Eagan, MN (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Scynexis, Inc., Research Triangle Park, NC (US);
Abstract
Novel derivatives of enfumafungin are disclosed herein, along with their, pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.