The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8222217 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 17, 2012

Filed:

May. 30, 2008
Applicants:

Ezio Ghigo, Turin, IT;

Riccarda Granata, Turin, IT;

Aart Jan Van Der Lely, Bergschenhoek, NL;

Inventors:

Ezio Ghigo, Turin, IT;

Riccarda Granata, Turin, IT;

Aart Jan Van Der Lely, Bergschenhoek, NL;

Assignee:

Alize Pharma SAS, Ecully, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/08 (2006.01); A61K 38/12 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

An isolated polypeptide comprising any amino acid fragment of unacylated ghrelin or any analog thereof, wherein the polypeptide has an activity selected from the group consisting of a) decreasing blood glucose levels; b) increasing insulin secretion an/or sensitivity; c) binding to insulin-secreting cells; and d) promoting survival of insulin-secreting cells. As well as the use of the polypeptide in the treatment of a disorder associated with impaired glucose metabolism.


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