The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
Feb. 27, 2009
Jeffrey M. Jonas, Bryn Mawr, PA (US);
Roger A. Rajewski, Lawrence, KS (US);
Bala Subramaniam, Lawrence, KS (US);
Katherine F. Terranova, Overland Park, KS (US);
Jeffrey M. Jonas, Bryn Mawr, PA (US);
Roger A. Rajewski, Lawrence, KS (US);
Bala Subramaniam, Lawrence, KS (US);
Katherine F. Terranova, Overland Park, KS (US);
Abstract
The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.