The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
Oct. 08, 2009
Marion T. Kasaian, Cambridge, MA (US);
Lioudmila Gennadievna Tchistiakova, Andover, MA (US);
Geertruida Machteld Veldman, Sudbury, MA (US);
Kimberly Ann Marquette, Somerville, MA (US);
Xiang-yang Tan, Reading, MA (US);
Debra D. Donaldson, Medford, MA (US);
Laura Long Lin, Weston, MA (US);
Tania Shane, Newton, MA (US);
Amy Sze Pui Tam, Medford, MA (US);
Eric Feyfant, Lexington, MA (US);
Nancy L. Wood, Somerville, MA (US);
Lori J. Fitz, Somerville, MA (US);
Angela M. Widom, Acton, MA (US);
Kevin D. Parris, Auburndale, MA (US);
Samuel J. Goldman, Acton, MA (US);
Jose W. Saldanha, Enfield, GB;
Marion T. Kasaian, Cambridge, MA (US);
Lioudmila Gennadievna Tchistiakova, Andover, MA (US);
Geertruida Machteld Veldman, Sudbury, MA (US);
Kimberly Ann Marquette, Somerville, MA (US);
Xiang-Yang Tan, Reading, MA (US);
Debra D. Donaldson, Medford, MA (US);
Laura Long Lin, Weston, MA (US);
Tania Shane, Newton, MA (US);
Amy Sze Pui Tam, Medford, MA (US);
Eric Feyfant, Lexington, MA (US);
Nancy L. Wood, Somerville, MA (US);
Lori J. Fitz, Somerville, MA (US);
Angela M. Widom, Acton, MA (US);
Kevin D. Parris, Auburndale, MA (US);
Samuel J. Goldman, Acton, MA (US);
Jose W. Saldanha, Enfield, GB;
Wyeth LLC, Madison, NJ (US);
Abstract
This application relates to antibodies, e.g., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e.g., a human patient, one or more IL-13-associated disorders, e.g., respiratory disorders (e.g., asthma); atopic disorders (e.g., allergic rhinitis); inflammatory and/or autoimmune conditions of the skin (e.g., atopic dermatitis), and gastrointestinal organs (e.g., inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.