The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2012
Filed:
May. 26, 2008
Junya Satoh, Tokyo, JP;
Takahiro Ichi, Tokyo, JP;
Shunji Maniwa, Tokyo, JP;
Asahi Kasei Medical Co., Ltd., Tokyo, JP;
Abstract
A polysulfone-based blood treatment membrane that exhibits excellent antioxidant properties, excellent long-term storage stability, and a practical strength, and ensures high productivity, a polysulfone-based blood treatment membrane that exhibits excellent antioxidant properties and long-term storage stability, rarely allows endotoxins to enter a treatment liquid, exhibits a practical strength, and ensures high productivity, and a method of producing the same. A polysulfone-based blood treatment membrane includes a polysulfone-based resin, a hydrophilic polymer, and a lipophilic antioxidant, the membrane containing the lipophilic antioxidant in an amount of 30 to 76 mg per gram of the membrane, and the total amount of the lipophilic antioxidant present on the surface of the membrane being 4 to 25 mg per gram of the membrane. Another polysulfone-based blood treatment membrane contains a lipophilic antioxidant in an amount of 30 to 76 mg per gram of the membrane, wherein the inner surface of the membrane has a TOF-SIMS normalized peak intensity of the lipophilic antioxidant of 1.8.times.10.sup.-4 or more, and the outer surface of the membrane has a TOF-SIMS normalized peak intensity of the lipophilic antioxidant of 2.4.times.10.sup.-4 or more. A method of producing a polysulfone-based blood treatment membrane that includes a polysulfone-based resin, a hydrophilic polymer, and a lipophilic antioxidant includes producing a membrane intermediate that contains the lipophilic antioxidant in an amount of 30 to 76 mg per gram of the membrane intermediate, and heating the membrane intermediate at 100 to 180.degree. C. for 0.1 to 360 minutes in a dry state.