The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Jan. 11, 2008
Joerg Bewersdorf, Bar Harbor, ME (US);
Michael Darin Mason, Orrington, ME (US);
Sam T. Hess, Stillwater, ME (US);
Joerg Bewersdorf, Bar Harbor, ME (US);
Michael Darin Mason, Orrington, ME (US);
Sam T. Hess, Stillwater, ME (US);
The Jackson Laboratory, Bar Harbor, ME (US);
University of Maine, Orono, ME (US);
Abstract
A method of performing 3D photoactivation microscope imaging includes providing a sample having a plurality of probes, each of the plurality of probes including a photo-activatable material. Probes from the plurality of probes are activated to form a sparse subset of probes, the sparse subset of probes having probes that are spatially separated by at least a microscope resolution. The sample is illuminated with a readout light source, and light emitted from activated probes is detected. Based on the light emission detected from the activated probes, localized three-dimensional positions of the activated probes are obtained.