The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2012

Filed:

Feb. 16, 2011
Applicants:

Yong MI Choi-sledeski, Bridgewater, NJ (US);

Nakyen Choy, Bridgewater, NJ (US);

Gregory Bernard Poli, Bridgewater, NJ (US);

John J. Shay, Jr., Bridgewater, NJ (US);

Patrick Wai-kwok Shum, Bridgewater, NJ (US);

Adam W. Sledeski, Bridgewater, NJ (US);

Inventors:

Yong Mi Choi-Sledeski, Bridgewater, NJ (US);

Nakyen Choy, Bridgewater, NJ (US);

Gregory Bernard Poli, Bridgewater, NJ (US);

John J. Shay, Jr., Bridgewater, NJ (US);

Patrick Wai-Kwok Shum, Bridgewater, NJ (US);

Adam W. Sledeski, Bridgewater, NJ (US);

Assignee:

Sanofi, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.


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