The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Nov. 22, 2006
Applicants:
Gunnar Glad, Uppsala, SE;
Jean-luc Maloisel, Uppsala, SE;
Nicolas Thevenin, Uppsala, SE;
Inventors:
Assignee:
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 303/02 (2006.01); C07H 1/00 (2006.01); C08F 8/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed is a method for activating a solid support material with epoxy groups and for immobilizing ligands thereon, utilizing phase transfer catalytic conditions. The method permits the introduction of epoxy groups and specific nucleophilic ligands on the support material with a high level of substitution. Furthermore, the invention provides a general method for immobilizing a ligand for use in a wide variety of chromatographic separation procedures such as ion exchange chromatography, hydrophobic interaction chromatography (HIC), reverse phase chromatography (RPC), or affinity chromatography.