The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2012

Filed:

Jan. 07, 2010
Applicants:

Jing Zhang, Parsippany, NJ (US);

Zhuming Zhang, Hillsborough, NJ (US);

Inventors:

Jing Zhang, Parsippany, NJ (US);

Zhuming Zhang, Hillsborough, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); A61P 35/00 (2006.01); C07D 471/10 (2006.01); C07D 209/04 (2006.01); C07D 209/54 (2006.01); A61K 31/404 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided compounds of the formula or a pharmaceutically acceptable salt or ester thereof wherein X, Y, R, Rare as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.


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