The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2012

Filed:

Apr. 20, 2011
Applicants:

Maja Osmak, Zagreb, HR;

Slovenko Polanc, Ljubljana, SI;

Tamara Cimbora Zovko, Zagreb, HR;

Anamaria Brozovic, Zagreb, HR;

Marijan Kocevar, Ljubljana, SI;

Vita Majce, Ljubljana, SI;

Branko Alic, Ljubljana, SI;

Inventors:

Maja Osmak, Zagreb, HR;

Slovenko Polanc, Ljubljana, SI;

Tamara Cimbora Zovko, Zagreb, HR;

Anamaria Brozovic, Zagreb, HR;

Marijan Kocevar, Ljubljana, SI;

Vita Majce, Ljubljana, SI;

Branko Alic, Ljubljana, SI;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 245/24 (2006.01); A61K 31/655 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention refers to analogues of 1,3-bis(4-nitrophenyl)triazenes, their pharmaceutically acceptable salts and N-acyl derivatives for the treatment of different types of tumors. Said compounds show cytotoxicity at very low concentrations (IC0.22 to 12.8 μM), and good solubility. These compounds can be used in the treatment of tumor patients as single drugs or in combination with other cytostatics.


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