The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Oct. 06, 2006
Satish Kumar, Bareilly, IN;
Manish Virendrasingh Bais, Bareilly, IN;
Ranjit Singh Kataria, Bareilly, IN;
Mahendra Pal Yadav, Bareilly, IN;
Satish Kumar, Bareilly, IN;
Manish Virendrasingh Bais, Bareilly, IN;
Ranjit Singh Kataria, Bareilly, IN;
Mahendra Pal Yadav, Bareilly, IN;
Indian Council of Agricultural Research, New Delhi, IN;
Abstract
A short synthetic vector peptide of 25 residues has been developed comprising hydrophobic domain and a novel, nuclear localization signal for efficient delivery, devoid of any cytotoxicity. Using the vector peptide, the oligonucleotide/peptide complexes got delivered evenly in cytoplasm and nucleus in less than an hour and finally localizing completely into nucleus in two hours and protein (antibody) to cytoplasm within 1 hour in both primary (chicken embryo fibroblast) cells and established mammalian cell line (Vero cells).