The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Jun. 07, 2007
Nobuko Muraki, Otsu, JP;
Mitsuko Ideno, Otsu, JP;
Kinuko Nagamine, Otsu, JP;
Fuyuko Takashima, Otsu, JP;
Eiji Kobayashi, Otsu, JP;
Akiko Kato, Otsu, JP;
Takahiro Marui, Otsu, JP;
Hiroaki Sagawa, Otsu, JP;
Tatsuji Enoki, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
Nobuko Muraki, Otsu, JP;
Mitsuko Ideno, Otsu, JP;
Kinuko Nagamine, Otsu, JP;
Fuyuko Takashima, Otsu, JP;
Eiji Kobayashi, Otsu, JP;
Akiko Kato, Otsu, JP;
Takahiro Marui, Otsu, JP;
Hiroaki Sagawa, Otsu, JP;
Tatsuji Enoki, Otsu, JP;
Ikunoshin Kato, Otsu, JP;
Takara Bio Inc., Otsu-shi, JP;
Abstract
A method of producing lymphocytes characterized by comprising the step of culturing lymphocytes in the presence of a modified recombinant fibronectin fragment which has overlapping parts of the heparin-binding domain of fibronectin. This method makes it possible to achieve a high cell proliferation rate. The lymphocytes obtained thereby are appropriately usable in, for example, adoptive immunotherapy and, therefore, expected as highly useful in the clinical field. Moreover, a novel modified recombinant fibronectin fragment is provided.