The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Jun. 18, 2009
Hélène Autefage, Toulouse, FR;
Sophie Cazalbou, Rebigue, FR;
Christèle Combes, Ramonville St Agne, FR;
Christian Rey, Aureville, FR;
Hélène Autefage, Toulouse, FR;
Sophie Cazalbou, Rebigue, FR;
Christèle Combes, Ramonville St Agne, FR;
Christian Rey, Aureville, FR;
Institut National Polytechnique de Toulouse, Toulouse Cedex, FR;
TEKNIMED, Vic-En-Bigorre Cedex, FR;
Abstract
The present invention relates to a porous biomaterials surface activation method by coating with a layer of apatitic nanocrystals in order to increase their surface reactivity. The method according to the invention is characterized by the following steps: a) preparing a nanocrystalline apatitic calcium phosphate analogous to bone mineral by mixing a calcium salt solution with a phosphate salt solution in a Ca/P ratio ranging between 1.3 and 2 at a temperature ranging between 0 and 60 ° C., b) slurrying the mixture obtained in step a) in an aqueous solution so as to obtain a fluid, homogeneous paste containing 80 to 98% of water, c) bringing a porous biomaterial into contact with the suspension obtained in step b), d) drying the porous biomaterial at a temperature below 100 ° C.