The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Jul. 21, 2008
Applicants:
Andrew G. Plaut, Lexington, MA (US);
Jiazhou Qiu, Westborough, MA (US);
Inventors:
Andrew G. Plaut, Lexington, MA (US);
Jiazhou Qiu, Westborough, MA (US);
Assignee:
Tufts Medical Center, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention discloses the use of bacterial IgA1 proteases to treat IgA1 deposition in tissue and organs. Bacterial IgA1 proteases specifically cleave IgA1 molecules and thus provide a means to specifically cleave and remove IgA1 depositions. Accordingly, therapeutic agents for the treatment of diseases characterized by IgA deposition are provided. In particular, therapeutic agents to treat IgA nephropathy, Dermatitis herpetiformis (DH), and Henoch-Schoenlein purpura (HS) are disclosed.