The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2012
Filed:
Sep. 06, 2006
Christoph Bremer, Münster, DE;
Carsten Höltke, Münster, DE;
Klaus Kopka, Münster, DE;
Michael Schäfers, Münster, DE;
Christoph Bremer, Münster, DE;
Carsten Höltke, Münster, DE;
Klaus Kopka, Münster, DE;
Michael Schäfers, Münster, DE;
Universitatskilinikum Munster, Munster, DE;
Abstract
The present invention relates to a endothelin receptor antagonist conjugate of the formula (I) wherein Ris an alkoxy group and one of Rand Rrepresents an alkoxy group and the other represents a group of the formula: (OCHCH)—NH—X, wherein n is an integer of 1 to 100 and X represents a fluorescent dye and tautomers thereof. Furthermore, the present invention relates to a diagnostic composition comprising the compounds of the invention. The present invention also relates to the use of the compounds of the invention for the preparation of a diagnostic composition for the diagnosis of cancer, the evaluation of cancer biology and/or monitoring of anticancer therapy. In a further aspect, the present invention relates to kits comprising the compounds of the invention.