The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2012

Filed:

Apr. 09, 2010
Applicants:

Yun Ding, Waltham, MA (US);

Reema K. Thalji, Collegeville, PA (US);

Joseph P. Marino, Jr., King of Prussia, PA (US);

Inventors:

Yun Ding, Waltham, MA (US);

Reema K. Thalji, Collegeville, PA (US);

Joseph P. Marino, Jr., King of Prussia, PA (US);

Assignee:

GlaxoSmithKline LLC., Philadelphia, PA (US);

Attorneys:
Int. Cl.
CPC ...
C07D 251/50 (2006.01); A61K 31/53 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/06 (2006.01); A61P 11/00 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme. Specifically, the invention is directed to (Cis)-N-{[4-cyano-2-(trifluoromethyl)phenyl]methyl}-3-{[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxamide; or a pharmaceutically acceptable salt thereof, and N-{[4-cyano-2-(trifluoromethyl)phenyl]methyl}-3-{[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxamide; or a pharmaceutically acceptable salt thereof.


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