The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8212014 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 03, 2012

Filed:

Aug. 04, 2006
Applicants:

Ichiro Hirao, Yokohama, JP;

Michiko Hirao, Yokohama, JP;

Shigeyuki Yokoyama, Yokohama, JP;

Inventors:

Ichiro Hirao, Yokohama, JP;

Michiko Hirao, Yokohama, JP;

Shigeyuki Yokoyama, Yokohama, JP;

Assignee:

Riken, Wako-shi, Saitama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); C12Q 1/68 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides nucleic acids based on novel artificial base pairing, as well as a preparation method and uses thereof. In the nucleic acids of the present invention, a nucleotide having a substituted or unsubstituted 2-formyl-1H-pyrrol-1-yl group as a base forms a base pair with a nucleotide having a 6-substituted 9H-purin-9-yl group as a base. The inventive method for preparing a nucleic acid comprises effecting transcription, reverse transcription or replication by using, as a template, a nucleic acid incorporating a nucleotide having a substituted or unsubstituted 2-formyl-1H-pyrrol-1-yl group as a base, so that the nucleotide having a 6-substituted 9H-purin-9-yl group is incorporated at a site complementary to the nucleotide having a substituted or unsubstituted 2-formyl-1H-pyrrol-1-yl group.


Find Patent Forward Citations

Hirao, Ichiro. (2012). Artificial base pairs and uses thereof (U.S. Patent No. 8212014). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8212014

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