The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8211872 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 03, 2012

Filed:

Oct. 24, 2008
Applicant:

Elaine A. Delack, Stanwood, WA (US);

Inventor:

Elaine A. Delack, Stanwood, WA (US);

Assignee:

MedDEV, Inc., Bellingham, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 57/00 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for treating the symptoms of multiple sclerosis and related neurodegenerative conditions, using a histamine compound that is methylated in vitro prior to being introduced into the body of the patient. The histamine compound is suitably histamine diphosphate, and may be methylated in vitro by mixing in combination with at least one thiol compound in the presence of at least one methyl group donor compound. The thiol compound is suitably L-reduced glutathione and the methyl group donor is suitably betaine hydrochloride. The compounds are mixed vigorous in an acid environment, to create a shearing force that facilitates exchange of the methyl group from the donor compound to the histamine diphosphate. The resulting methylated histamine compound is suitably administered to the patient by transdermal application. The method also provides a medicament for treatment the symptoms of multiple sclerosis and related neurodegenerative conditions, and a method for preparation of such a medicament.


Find Patent Forward Citations

Delack, Elaine. (2012). Method and composition for treatment of multiple sclerosis and related neurodegenerative conditions (U.S. Patent No. 8211872). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8211872

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