The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2012
Filed:
May. 03, 2007
Jean-paul Di Rago, Sainte-Helene, FR;
Malgorzata Rak, Checiny, PL;
Roza Kucharczyk, Warsaw, PL;
Emmanuel Tetaud, Pessac, FR;
Stephane Duvezin-caubet, Mimbaste, FR;
Jean-Paul Di Rago, Sainte-Helene, FR;
Malgorzata Rak, Checiny, PL;
Roza Kucharczyk, Warsaw, PL;
Emmanuel Tetaud, Pessac, FR;
Stephane Duvezin-Caubet, Mimbaste, FR;
Universite Victor Segalen Bordeaux 2, Bordeaux, FR;
Centre National de la Recherche Scientifique, Paris, FR;
Abstract
Modified yeast cells comprising at least one mutation of the tryptophan 136 (W), leucine 183 (L), or leucine 247 (L) codon of the mitochondrial ATP6 gene, responsible for NARP syndrome in humans and uses thereof for screening for medicaments that act against mitochondrial pathologies involving a deficiency in ATP production via the oxidative phosphorylation pathway, such as NARP syndrome.