The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2012

Filed:

Apr. 29, 2011
Applicants:

Fernando Jose Rebelo DO Couto, Pleasanton, CA (US);

Kristin Beth Hendricks, San Carlos, CA (US);

Stacey Ellen Wallace, Sunnyvale, CA (US);

Inventors:

Fernando Jose Rebelo Do Couto, Pleasanton, CA (US);

Kristin Beth Hendricks, San Carlos, CA (US);

Stacey Ellen Wallace, Sunnyvale, CA (US);

Assignee:

Epitomics, Inc., Burlingame, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides monoclonal antibodies that neutralize TNFα activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal antibodies having CDR regions derived from those rabbit monoclonal antibodies. In certain embodiments, the monoclonal antibodies may be humanized. Methods of using the subject antibodies to inhibit TNFα activity, methods of treatment using those antibodies and kits containing the same are also provided. The invention finds use in a variety of research and medical applications.


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