The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2012
Filed:
Apr. 04, 2007
Keat (Thomas) H. Teoh, Jonesboro, AR (US);
Darwin R. Reed, Saskatoon, CA;
Devin R. Polichuk, Saskatoon, CA;
Patrick S. Covello, Saskatoon, CA;
Keat (Thomas) H. Teoh, Jonesboro, AR (US);
Darwin R. Reed, Saskatoon, CA;
Devin R. Polichuk, Saskatoon, CA;
Patrick S. Covello, Saskatoon, CA;
National Research Council of Canada, Ottawa, Ontario, CA;
Abstract
Isolated nucleic acid molecules cloned fromencode artemisinic aldehyde double bond reductase and artemisinic/dihydroartemisinic aldehyde dehydrogenase. Artemisinic aldehyde double bond reductase enzymatically reduces artemisinic aldehyde to dihydroartemisinic aldehyde. Artemisinic/dihydroartemisinic aldehyde dehydrogenase enzymatically oxidizes dihydroartemisinic aldehyde to dihydroartemisinic acid and artemisinic aldehyde to artemisinic acid. The nucleic acid molecules, and the enzymes encoded thereby, may be used in processes to produce dihydroartemsinic aldehyde, dihydroartemisinic acid or artemisinic acid in a host cell. Dihydroartemisinic acid is a late precursor to the a antimalarial compound artemisinin.