The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2012
Filed:
May. 01, 2009
Applicants:
Paul Hatala, Charlestown, MA (US);
William J. Issa, Avon, MA (US);
Inventors:
Paul Hatala, Charlestown, MA (US);
William J. Issa, Avon, MA (US);
Assignee:
Archemix Corp., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/34 (2006.01); C07H 1/06 (2006.01); C07K 1/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to methods for separating or purifying biopolymer conjugated molecules from unconjugated molecules. In particular, methods are described for purifying a PEGylated protein or oligonucleotide from an unPEGylated protein or oligonucleotide, respectively. The methods are quick and efficient separation methods because they do not require gradient chromatography, fractionation of an eluent or analysis of the eluted fractions. Further, the methods increase yield and purity of the biopolymer conjugated molecule.