The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2012
Filed:
Jul. 13, 2009
Satoshi Aoki, Tokyo, JP;
Ryosuke Munakata, Tokyo, JP;
Noriyuki Kawano, Tokyo, JP;
Kiyohiro Samizu, Tokyo, JP;
Hiromasa Oka, Tokyo, JP;
Takahiro Ishii, Tokyo, JP;
Takashi Sugane, Tokyo, JP;
Satoshi Aoki, Tokyo, JP;
Ryosuke Munakata, Tokyo, JP;
Noriyuki Kawano, Tokyo, JP;
Kiyohiro Samizu, Tokyo, JP;
Hiromasa Oka, Tokyo, JP;
Takahiro Ishii, Tokyo, JP;
Takashi Sugane, Tokyo, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
A compound which is useful as an active ingredient of a pharmaceutical composition for treating neuropathic pain is provided. The present inventors have made extensive studies on compounds having an FAAH inhibitory activity, and as a result, have found that an azole compound substituted with an N-(pyridine-3-yl)oxycarbonyl-piperidin-4-yl group and a phenyl group or a pharmaceutically acceptable salt thereof has an excellent FAAH inhibitory activity, thereby completing the present invention. The compound of the present invention is confirmed to have an excellent FAAH inhibitory activity and an antiallodynic effect in rat models with neuropathic pain, and thus is useful as an agent for preventing and/or an agent for treating neuropathic pain.