The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2012
Filed:
Jun. 07, 2005
Avigdor Scherz, Rehovot, IL;
Alexander Brandis, Rehovot, IL;
Yoram Salomon, Rehovot, IL;
Doron Eren, Netaim, IL;
Avraham Cohen, Tel Aviv, IL;
Avigdor Scherz, Rehovot, IL;
Alexander Brandis, Rehovot, IL;
Yoram Salomon, Rehovot, IL;
Doron Eren, Netaim, IL;
Avraham Cohen, Tel Aviv, IL;
Yeda Research and Development Co., Ltd., Rehovot, IL;
Abstract
The invention provides cationic tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one positively charged group and/or at least one basic group that is converted to a positively charged group under physiological conditions, preferably Bchls having an onium group derived from a N-containing aliphatic or heterocyclic radical such as ammonium, guanidinium, imidazolium, pyridinium, and the like or a phosphonium, arsonium, oxonium, sulfonium, selenonium, telluronium, stibonium, or bismuthonium group, or a basic group that is converted to such onium groups under physiological conditions, said groups being bound to one or more of the positions 17<3>, 13<3> and 3<2> of the Bchl molecule by ester or amide bond. The Bchls are useful for photodynamic therapy and diagnosis.