The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2012

Filed:

Nov. 22, 2008
Applicants:

Chao-wei Liao, Shin-Chu, TW;

Chung-nan Weng, MiaoliCounty, TW;

Hsiu-kang Chang, Taipei, TW;

Inventors:

Chao-Wei Liao, Shin-Chu, TW;

Chung-Nan Weng, MiaoliCounty, TW;

Hsiu-Kang Chang, Taipei, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); A61K 39/104 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fusion antigen used as vaccine and method of making them. The method includes: (1) selecting a segment of a virus protein sequence that contains a least one epitope; (2) engineering a DNA fragment encoding the selected segment of the virus protein; (3) inserting the DNA fragment into aExotoxin A (PE) vector to obtain a chimeric gene plasmid, and expressing the chimeric gene plasmid in a host cell to obtain the chimeric vaccinal virus antigen. The PE vector contains a PE fragment, which has a binding domain and a translocating domain, and a carboxyl terminal moiety, which includes an endoplasmic reticulum retention sequence. The DNA fragment encoding the selected segment of the virus protein is inserted between the PE fragment and the carboxyl terminal moiety.


Find Patent Forward Citations

Liao, Chao-Wei. (2012). Fusion antigen used as vaccine and method of making them (U.S. Patent No. 8206950). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8206950

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