The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2012

Filed:

Sep. 30, 2002
Applicants:

Indu Parikh, Chapel Hill, NC (US);

Ulagaraj Selvaraj, Apex, NC (US);

Inventors:

Indu Parikh, Chapel Hill, NC (US);

Ulagaraj Selvaraj, Apex, NC (US);

Assignee:

Jagotec AG, Muttenz, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/16 (2006.01); A61K 9/64 (2006.01); A61K 9/52 (2006.01); A61K 47/32 (2006.01); A61F 2/00 (2006.01); A61B 8/00 (2006.01); B29B 9/00 (2006.01); B01F 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a composition comprising microparticles of a water-insoluble or poorly soluble compound, at least one phospholipid, and at least one surfactant, produced by applying an energy to a mixture comprising particles of the compound, the at least one phospholipid, and the at least one surfactant so as to obtain the microparticles. The invention also provides a process for preparing microparticles of a water-insoluble or poorly soluble compound. The process includes mixing particles of a water-insoluble or poorly soluble compound with at least one phospholipid and at least surfactant to form a mixture and applying energy to the mixture sufficient to produce microparticles of the compound. The methods of the invention allow for the production of microparticles smaller than particles produced through previously known methods and the microparticles exhibit advantageous properties including remarkable resistance to particle size growth during storage.


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